Lower limb giant plexiform neurofibroma: preoperative evaluation and surgical planning

Riccardo Villani, Veronica Vietti Michelina, Erich Fabbri, Daniela Tassone, Paolo Giovanni Morselli


Few cases of lower limb giant plexiform neurofibroma have been reported in literature and there are no available guidelines for defining its preoperative evaluation and surgical approach. Lower limb giant plexiform neurofibroma is a rare condition that requires clinical and radiological preoperative evaluation, mainly with MRI. Surgery is the only treatment with no preoperative trans-arterial embolization or vessel ligation. Early excision of superficial lesions may prevent further progression.


Lower limb gigantism, Plexiform neurofibromas, MRI

Full Text: